A new study documents an increased incidence of silicosis, which progressed rapidly to massive pulmonary fibrosis in a significant proportion…
Medicinal leech genome sequenced
A new study offers insights into the powerful anticoagulants contained in the saliva of leeches most often used in medical…
COVID-19 toll in nursing homes linked to staffing levels and quality
A new study shows that residents of long-term care facilities with lower nurse staffing levels, poorer quality scores, and higher…
Open-source machine learning tool connects drug targets with adverse reactions
Scientists develop AI-based tool to predict adverse drug events. Such events are responsible for some 2 million U.S. hospitalizations per…
“We Signed Up for This!” — Student and Trainee Responses to the Covid-19 Pandemic
On January 20, 2020, the first U.S. case of Covid-19 was reported in Washington State. Substantial challenges lay ahead. Covid-19…
Audio Interview: A Look at SARS-CoV-2 Transmission
The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission,…
Amplifying RNA Vaccine Development
In the early 1990s, direct injection of nucleic acids (RNA or DNA) into the muscles of mice led to in…
Empirical Antituberculosis Therapy in Advanced HIV Disease — Too Much, Too Late
Despite the extraordinary advances in treating human immunodeficiency virus (HIV) infection during the past two decades, mortality, especially in resource-limited…
Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults
Tuberculosis is the 10th leading cause of death worldwide and the main cause of death from a single infectious agent.…
Reconsidering the Trade-offs of Prostate Cancer Screening
After the widespread adoption of prostate-specific antigen (PSA) screening in the early 1990s, prostate cancer diagnoses increased rapidly while death…