A research team has now removed a major barrier for the use of kidney organoids as a tool to model kidney diseases, test drug toxicities and eventually for the creation of organ replacements, the lack of a pervasive blood vessel system (vasculature). The team solved this problem with a powerful new approach that exposes stem cell-derived kidney organoids to fluidic shear stress and thus enables them to vascularize and mature further than they could before.
Engineered miniature kidneys come of age
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