Irritable bowel syndrome

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by chronic abdominal pain associated with a change in frequency and form of stool. IBS is common, with a population prevalence of around 10%, and causes a reduction in quality of life. Its pathophysiology remains incompletely understood, although abnormal communications within the brain–gut axis are considered to be important. IBS can be subclassified according to predominant bowel habit and/or pain. Treatments are directed towards improving symptoms and are multifaceted.