Researchers combined two different analysis techniques into one method, to simultaneously analyze how chromosomes, along with their epigenetic features, are compacted inside of single human brain cells. The method, called single-nucleus methyl-3C sequencing, not only enabled them to identify gene regulatory elements in distinct cell types, but also paves the way toward a new understanding of how some cells become dysregulated to cause disease.
Scientists develop technique to reveal epigenetic features of cells in the brain
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