Sarcopenia describes the accelerated loss of skeletal muscle, manifesting as a combination of low muscle strength and low muscle mass. Frailty can be described as the collective deterioration of multiple body systems, leading to reduced ability to maintain homeostasis and respond to physiological stresses placed upon the body. Frailty and sarcopenia are common, especially in hospitalized older people, and also occur at younger ages in the setting of multiple long-term conditions (multimorbidity).
The ageing syndromes of sarcopenia and frailty
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